Biology Digest

 

Coming join us in the lab to see how scientists make the proteins that players designed in Foldit. It all begins with an envelope full of custom DNA. 0:00 ​​ – intro 0:29 – in the lab 5:01 – design of the month 9:48 – outro You don't have to be a scientist to do science. Download and play Foldit and you can help researchers discover new drugs for cancer, antivirals, and more. The most promising solutions are being manufactured and tested at the University of Washington Institute for Protein Design in Seattle. Foldit is FREE and not-for-profit: https://fold.it/​​ This video features Foldit scientist Brian Koepnick, PhD. It was produced by Ian Haydon. Note: Foldit is an interactive computer game and not a distributed computing project. If you would like to donate spare CPU cycles to science, please check out the Rosetta@Home project on BOINC at https://boinc.bakerlab.org/  

  Seattle-based   Cyrus Biotechnology   is entering a protein engineering collaboration with Boston-based   Selecta Biosciences   that could pull in up to $1.5 billion for the University of Washington spinout. The partnership will support the development of new agents for immune-related conditions,   the companies announced   this week. The partnership includes an undisclosed up-front payment and is worth up to $1.5 billion for Cyrus — if the deal hits certain drug discovery, development and sales milestones. The partnership’s lead program will combine an immune modulating agent developed by Selecta with a protein called IL-2, being engineered by Cyrus. Cyrus CEO Lucas Nivon. (Cyrus Photo) Cyrus is enhancing IL-2 through its protein engineering software and through testing at the laboratory bench. Cyrus can engineer therapeutic proteins with properties such as greater stability in the body, using its software tools originating from the UW’s Institute for Protein Design. The new partner

What we found in the lab wasn't what we expected — but it can tell us how to move forward. And that is science in action. 0:00 ​​ – intro 0:25 – LAB RESULT: PART 1 3:10 – LAB RESULT: PART 2 6:28 — PUZZLE UPDATES 7:03 – DESIGN OF THE MONTH 9:58 ​ – outro You don't have to be a scientist to do science. Download and play Foldit and you can help researchers discover new antiviral drugs that might stop coronavirus. The most promising solutions are being manufactured and tested at the University of Washington Institute for Protein Design in Seattle. Foldit is FREE and not-for-profit: https://fold.it/​​ This video features Foldit scientist Brian Koepnick, PhD. It was produced by Ian Haydon. Note: Foldit is an interactive computer game and not a distributed computing project. If you would like to donate spare CPU cycles to science, please check out the Rosetta@Home project on BOINC at https://boinc.bakerlab.org/   Crowded cell animation by BioVisions: https://www.youtube.com/w

We've got a new way for you to hone your folding skills! Step into the Dojo to bridge the gap between Foldit's simple tutorial levels and our more hardcore science puzzles. 0:00 ​​ – intro 0:22 – DOJO MODE 1:30 – NEW LAB RESULTS 3:36 — PUZZLE UPDATES 5:06 – DESIGN OF THE MONTH 7:35 ​ – outro You don't have to be a scientist to do science. Download and play Foldit and you can help researchers discover new antiviral drugs that might stop coronavirus. The most promising solutions are being manufactured and tested at the University of Washington Institute for Protein Design in Seattle. Foldit is FREE and not-for-profit: https://fold.it/​​ This video features Foldit scientist Brian Koepnick, PhD. It was produced by Ian Haydon. Note: Foldit is an interactive computer game and not a distributed computing project. If you would like to donate spare CPU cycles to science, please check out the Rosetta@Home project on BOINC at https://boinc.bakerlab.org/ Astrovirus image by G

  We have some exciting news to share after testing some of your protein designs in the lab. Plus we've got new puzzles and a fresh Design of the Month. - - - - - You don't have to be a scientist to do science. Download and play Foldit and you can help researchers discover new antiviral drugs that might stop coronavirus. The most promising solutions are being manufactured and tested at the University of Washington Institute for Protein Design in Seattle. Foldit is FREE and not-for-profit: https://fold.it/​ This video features Foldit scientist Brian Koepnick, PhD. It was produced by Ian Haydon. - - - - - Note: Foldit is an interactive computer game and not a distributed computing project. If you would like to donate spare CPU cycles to science, please check out the Rosetta@Home project on BOINC at https://boinc.bakerlab.org/

  In this update the foldit crew does an update on the software on Deep mind and latest analysis on the  protein folding in relation to SARS-CoV-2 and MERS binder design as of New Years weekend 2021. This video will explain the folding mechanisms of the protein of interest in detail in relation to the folding project on foldit.