Biology Digest

  OLYMPIA, Wash.  -  Washington state   health officials are on heightened alert as tuberculosis (TB) cases are on the rise.  According to the Washington State Department of  Health , widespread disruptions in public health, healthcare services and missed TB diagnoses, because symptoms are similar between COVID-19 and TB, may  have contributed to the rise locally and globally.  In 2020, reported cases were down but officials said efforts to prevent COVID-19 may have reduced the spread or may have decreased due to delayed or missed TB diagnoses. Some people with TB may have also been misdiagnosed as having COVID-19.  In 2021, there were 199 reported cases of TB, which was a 22% increase from 2020. So far in 2022, 70 cases have been reported.  The DOH said 17 new cases all have connections with each other and several state prisons, which makes it the largest outbreak in the last two decades.  "It’s been 20 years since we saw a cluster of TB cases like this," says Tao Sheng Kwan

  E leven countries, including the U.S., have reported a total of 169 cases of severe acute hepatitis in healthy children aged 1 month to 16 years old, with the largest outbreak in the U.K. At least 17 children have required liver transplants and one patient has died, according to the WHO. The World Health Organization and the U.S. Centers for Disease Control and Prevention believe the outbreak might be linked to adenovirus, though investigations are continuing. In the past, adenoviruses have been rarely associated with hepatitis in children with weak immune systems but not in healthy ones. © Provided by CNBC Adenovirus (highly contagious virus). Image made from a transmission electron microscopy view. An outbreak of severe hepatitis in healthy children that has caused liver failure in some kids might be linked to adenovirus infection, though further investigation is needed, World Health Organization officials said on Thursday. Eleven countries, including the U.S., have reported at lea

Collaborators are now testing VHL ligand designs in the lab, and new software features put the focus on rotatable bonds to help us create more effective molecules. 0:00 ​​ – intro 0:20 – Testing small molecule designs 3:24 – Puzzle Updates 4:34 – Design of the Month 8:58 – outro You don't have to be a scientist to do science. Download and play Foldit and you can help researchers discover new drugs for cancer, antivirals, and more. The most promising solutions are being manufactured and tested at the University of Washington Institute for Protein Design in Seattle. Foldit is FREE and not-for-profit: https://fold.it/​​ This video features Foldit scientists Brian Koepnick, PhD. It was produced by Ian Haydon. Note: Foldit is an interactive computer game and not a distributed computing project. If you would like to donate spare CPU cycles to science, please check out the Rosetta@Home project on BOINC at https://boinc.bakerlab.org/  

Scientists can now make proteins that bind a bunch of different targets. How did they do it — and what does this breakthrough mean for Foldit? In this video, we breakdown a recent breakthough in protein design.

(CNN)In 2003, the Human Genome Project made history when it sequenced 92% of the human genome. But for nearly two decades since, scientists have struggled to decipher the remaining 8%. Now, a team of nearly 100 scientists from the Telomere-to-Telomere (T2T) Consortium has unveiled the complete human genome -- the first time it's been sequenced in its entirety, the researchers say. "Having this complete information will allow us to better understand how we form as an individual organism and how we vary not just between other humans but other species," Evan Eichler, a Howard Hughes Medical Institute investigator at the University of Washington and the research leader, said Thursday. The new research introduces 400 million letters to the previously sequenced DNA -- an entire chromosome's worth. The full genome will allow scientists to analyze how DNA differs between people and whether these genetic variations play a role in disease. The research, published in the journal

SAN BRUNO (KRON) – The 44 acres the Tanforan mall in San Bruno sits on has been sold to a real estade developer. Alexandria Real Estate has purchased three different sections of the Tanforan site for roughly $300 million. They plan to put in a life sciences campus and office space. There could also be housing, which is something the city of San Bruno was hoping for as it looked for someone to redevelop this location. Now, the Tanforan mall has been here since the 1970s. It was redeveloped in the early 2000s. And as it changes ownerships the people who live nearby are concerned about what this could mean for the people who work here and the future of this area. So far, we have not seen any specific details on what Alexandria Real Estate plans to do here, and certainly that will be an ongoing conversation with the county and the city of San Bruno in the months and years ahead. https://www.kron4.com/news/bay-area/peninsulas-tanforan-mall-to-become-biotech-office-space/ Congrats and hope f