OpenVaccine Updates: How Eterna players designed superfolder mRNAs and how Stanford researchers tested them - Hannah Wayment-Steele, PhD The first authorized COVID-19 vaccines were based on messenger RNA molecules that promote translation of SARS-CoV-2 antigen proteins. However, these vaccines have been logistically problematic for delivery to developing countries and to rural populations in developed countries. We will talk about how Eterna players designed "superfolder" mRNAs that were predicted to be more resistant to degradation, how researchers at the Das and Barna groups at Stanford validated their increased stability and translation, and what the next frontiers are for designing improved RNA vaccines.
Pfizer said an updated version of its COVID-19 vaccine will be 'ready in 100 days' if the new Omicron variant is resistant to its current vaccine
Pfizer said it will be able to manufacture and distribute an updated version of its COVID-19 vaccine within 100 days if the new variant Omicron is found to be resistant to its current vaccine. Scientists first detected the new variant in South Africa. It has since spread to several other countries, including Israel and Belgium, prompting a spate of travel restrictions across Europe, Asia, and North America , Insider's Aria Bendix reported . A health official said on Saturday that two cases of the variant have been detected in the UK . The variant itself has multiple mutations that might make it easier for it to evade antibodies that developed in the body after receiving a COVID-19 vaccine. The mutations might also cause the variant to spread easily — even among vaccinated people . The World Health Organization has labeled Omicron a " variant of concern ," a distinction given to the most threatening coronavirus variants. Delta, the v...
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