Chagas disease: New study to confirm the effectiveness of a shorter treatment

A clinical trial has been launched in Argentina to see if a shorter regimen of the drug benznidazole has the potential to become a new standard treatment for Chagas disease to treat adult patients in the chronic phase of the disease, with fewer side effects.

The hope with a shorter regimen is to increase adherence to treatment, improve the overall risk profile versus the benefits of treatment, and expand treatment coverage.

Approved by the regulatory agency ANMAT, the NuestroBen clinical trial will be carried out at six sites in the cities of Buenos Aires, Corrientes, and Santiago del Estero. It is led by the Drugs for Neglected Diseases initiative (DNDi), in partnership with Laboratorio ELEA PHOENIX and the Mundo Sano Foundation, under the supervision of Argentina’s Ministry of Health.

‘We carried out the first controlled study in Bolivia between 2016 and 2018 to assess the efficacy of various regimens with benznidazole. We concluded that a two-week treatment is as effective as an eight-week treatment, and none of the patients discontinued the treatment due to side effects,’ said Sergio Sosa Estani, Head of DNDi’s Chagas Clinical Programme.

http://outbreaknewstoday.com/chagas-disease-new-study-to-confirm-the-effectiveness-of-a-shorter-treatment-35874/

Comments

Pfizer said an updated version of its COVID-19 vaccine will be 'ready in 100 days' if the new Omicron variant is resistant to its current vaccine

Pfizer said it will be able to manufacture and distribute an updated version of its COVID-19 vaccine within 100 days if the new variant Omicron is found to be resistant to its current vaccine. Scientists first detected the new variant in South Africa. It has since spread to several other countries, including Israel and Belgium, prompting a spate of travel restrictions across Europe, Asia, and North America , Insider's Aria Bendix reported . A health official said on Saturday that two cases of the variant have been detected in the UK . The variant itself has multiple mutations that might make it easier for it to evade antibodies that developed in the body after receiving a COVID-19 vaccine. The mutations might also cause the variant to spread easily — even among vaccinated people . The World Health Organization has labeled Omicron a " variant of concern ," a distinction given to the most threatening coronavirus variants. Delta, the v...

Texas governor bans vaccine passports from being required in state ABC News

Thats Right States like Texas and Florida got the Vaccine Passport Conspiracy from Del Bigtree. https://abc7.com/politics/texas-governor-bans-vaccine-passport-requirement-in-state/10491161/ AUSTIN, Texas -- Gov. Greg Abbott issued an executive order Tuesday morning prohibiting state agencies or political subdivisions in Texas from creating a "vaccine passport" requirement. Conversation has grown around vaccine passports recently as an option that can be used for travel or even eating out . They are typically described as an app with a code that verifies if someone has been vaccinated or recently tested negative for COVID-19. They're already in use in Israel, and in development in parts of Europe. But Abbott shut that down as an option in the Lone Star State with Executive Order No. GA - 35 also prohibiting "organizations receiving public funds from requiring consumers to provide documentation of vaccine status in order to receive any service or enter any place....

Biology Digest

Search This Blog